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Fig. 1 | BMC Molecular and Cell Biology

Fig. 1

From: mTOR signaling pathway regulation HIF-1 α effects on LPS induced intestinal mucosal epithelial model damage

Fig. 1

Confirmation of the optimal concentrations of LPS, DMOG and BAY 87-2243 for Caco-2 cells. (A-B) Effect of different concentrations of LPS on the viability of Caco-2 cells and the optimal concentration of LPS for this study was 600ug/ml. (C) Effect of different concentrations of DMOG on the viability of Caco-2 cells. (D) Effect of different concentrations of DMOG on the expression of HIF-1α in Caco-2 cells. (E) Effect of different concentrations of BAY 87-2243 on the viability of Caco-2 cells. (F) Effect of different concentrations of BAY 87-2243 on the expression of HIF-1α in Caco-2 cells. Optimal concentrations for DMOG and BAY 87-2243 were 104 nM and 10 nM respectively. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001 vs. 0 nM

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BMC Molecular and Cell Biology

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