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Figure 3 | BMC Cell Biology

Figure 3

From: Importin alpha binding and nuclear localization of PARP-2 is dependent on lysine 36, which is located within a predicted classical NLS

Figure 3

Leptomycin B does not alter localization of the PARP-2 mutant K36/37R. HEK293T cells were transfected with HA-tagged wild type (wt) PARP-2 (upper panel) or with the mutant K36/37R (lower panel) and treated with Leptomycin B (LMB) to inhibit nuclear export, followed by immunofluorescence as described in Fig. 2. Representative images are presented.

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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