Figure 2

Screening of transgenic mice. Southern analysis was performed using mouse genomic DNA extracted from the tail of potential Rab27a^T23N and Rab27a^N133I transgenics. Each well contains genomic DNA extracted from an individual mouse tail biopsy and electrophoresed on an agarose gel as described under "Methods". The band around 3.4 kb suggests the presence of an array of transgenes.