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Table 1 Summary of the cytostatic activities of mutant TC14-3s.

From: Tunicate cytostatic factor TC14-3 induces a polycomb group gene and histone modification through Ca2+ binding and protein dimerization

F65D

T69R

G70R

A103S

G105D

E106G

N109G

A111Q

G112S

K113S

N114E

K113SN114E

N136R

T144D

K145D

-

-

+++

+++

+++

-

++

+++

+++

++

++

+

+++

+++

+++

  1. +++, Cytostatic activities remained strong.
  2. ++, Cytostatic activities faintly decreased.
  3. +, Cytostatic activities were weakened to a large extent.
  4. -, Cytostatic activities were almost lost.