Figure 6From: Myotubularin family phosphatase ceMTM3 is required for muscle maintenance by preventing excessive autophagy in Caenorhabditis elegansKnockdown of ceMTM3 does not aggravate the abnormalities of muscle wasting in atg-18 mutant worms. VC893 atg-18 mutant worms were cultured on NGM plates containing E. coli cells carrying vector control or ceMTM3 RNAi from the time they were hatched from eggs. A. Moving tracks of day 5 N2 and VC893 worms cultured under the normal condition. B. Alexa Fluor 568 phalloidin staining of muscle fibers in control and ceMTM3 RNAi-treated worms of indicated ages. In comparison with normal N2 worms shown in Figure 1, VC893 worms displayed dimmer and less organized muscle fiber staining.Back to article page