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BMC Cell Biology

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  1. Content type: Research article

    Self-renewal and differentiation of embryonic stem cells (ESCs) is directed by biological and/or physical cues that regulate multiple signaling cascades. We have previously shown that mESCs seeded in a type I ...

    Authors: Olesja Hazenbiller, Neil A. Duncan and Roman J. Krawetz

    Citation: BMC Cell Biology 2017 18:32

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  2. Content type: Research article

    Altered expression of mRNA splicing factors occurs with ageing in vivo and is thought to be an ageing mechanism. The accumulation of senescent cells also occurs in vivo with advancing age and causes much degen...

    Authors: Eva Latorre, Vishal C. Birar, Angela N. Sheerin, J. Charles C. Jeynes, Amy Hooper, Helen R. Dawe, David Melzer, Lynne S. Cox, Richard G. A. Faragher, Elizabeth L. Ostler and Lorna W. Harries

    Citation: BMC Cell Biology 2017 18:31

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  3. Content type: Methodology article

    Generalized methods for understanding the cell biology of non-model species are quite rare, yet very much needed. In order to address this issue, we have modified a technique traditionally used in the biomedic...

    Authors: Benyamin Rosental, Zhanna Kozhekbaeva, Nathaniel Fernhoff, Jonathan M. Tsai and Nikki Traylor-Knowles

    Citation: BMC Cell Biology 2017 18:30

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  4. Content type: Research article

    Eph signaling is known to induce contrasting cell behaviors such as promoting and inhibiting cell adhesion/spreading by altering F-actin organization and influencing integrin activities. We have previously dem...

    Authors: Midori Mukai, Norihiko Suruga, Noritaka Saeki and Kazushige Ogawa

    Citation: BMC Cell Biology 2017 18:28

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  5. Content type: Research article

    Cartilage degradation is the significant pathological process in osteoarthritis (OA). Inflammatory cytokines, such as interleukin-1β (IL-1β), activate various downstream mediators contributing to OA pathology....

    Authors: Hao Wu, Zhanhai Yin, Ling Wang, Feng Li and Yusheng Qiu

    Citation: BMC Cell Biology 2017 18:29

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  6. Content type: Research article

    Endophytes have proven to be an invaluable resource of chemically diverse secondary metabolites that act as excellent lead compounds for anticancer drug discovery. Here we report the promising cytotoxic effect...

    Authors: Mytre Koul, Ashok Kumar, Ramesh Deshidi, Vishal Sharma, Rachna D. Singh, Jasvinder Singh, Parduman Raj Sharma, Bhahwal Ali Shah, Sundeep Jaglan and Shashank Singh

    Citation: BMC Cell Biology 2017 18:26

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    The Erratum to this article has been published in BMC Cell Biology 2017 18:27

  7. Content type: Research article

    Staufen2 (STAU2) is an RNA-binding protein involved in the post-transcriptional regulation of gene expression. This protein was shown to be required for organ formation and cell differentiation. Although STAU2...

    Authors: Rémy Beaujois, Elizabeth Ottoni, Xin Zhang, Christina Gagnon, Sami HSine, Stéphanie Mollet, Wildriss Viranaicken and Luc DesGroseillers

    Citation: BMC Cell Biology 2017 18:25

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  8. Content type: Research article

    Mesenchymal stem cells (MSCs) are multipotent stromal cells that have the ability to self-renew and migrate to sites of pathology. In vivo tracking of MSCs provides insights into both, the underlying mechanism...

    Authors: Yu Meng, Changzhen Shi, Bo Hu, Jian Gong, Xing Zhong, Xueyin Lin, Xinju Zhang, Jun Liu, Cong Liu and Hao Xu

    Citation: BMC Cell Biology 2017 18:24

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  9. Content type: Research article

    In Dictyostelium discoideum, vesicular transport of the adenylyl cyclase A (ACA) to the posterior of polarized cells is essential to relay exogenous 3′,5′-cyclic

    Authors: Satarupa Das, Joshua M. Parker, Can Guven, Weiye Wang, Paul W. Kriebel, Wolfgang Losert, Daniel R. Larson and Carole A. Parent

    Citation: BMC Cell Biology 2017 18:23

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  10. Content type: Research Article

    Autophagy is an inducible autodigestive process that allows cells to recycle proteins and other materials for survival during stress and nutrient deprived conditions. The kinase ULK1 is required to activate th...

    Authors: Wenjia Gan, Caiyun Zhang, Ka Yu Siu, Ayano Satoh, Julian A. Tanner and Sidney Yu

    Citation: BMC Cell Biology 2017 18:22

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  11. Content type: Research article

    Biomaterials are widely used to regenerate or substitute bone tissue. In order to evaluate their potential use for clinical applications, these need to be tested and evaluated in vitro with cell culture models...

    Authors: Raquel Núñez-Toldrà, Ester Martínez-Sarrà, Carlos Gil-Recio, Miguel Ángel Carrasco, Ashraf Al Madhoun, Sheyla Montori and Maher Atari

    Citation: BMC Cell Biology 2017 18:21

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  12. Content type: Research article

    External root resorption, commonly starting from cementum, is a severe side effect of orthodontic treatment. In this pathological process and repairing course followed, cementoblasts play a significant role. P...

    Authors: Yuyu Li, Zhiai Hu, Chenchen Zhou, Yang Xu, Li Huang, Xin Wang and Shujuan Zou

    Citation: BMC Cell Biology 2017 18:19

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  13. Content type: Research article

    Obesity is associated with multiple diseases, but it is unclear how obesity promotes progressive tissue damage. Recovery from injury requires repair, an energy-expensive process that is coupled to energy avail...

    Authors: Guanhua Xie, Marzena Swiderska-Syn, Mark L. Jewell, Mariana Verdelho Machado, Gregory A. Michelotti, Richard T. Premont and Anna Mae Diehl

    Citation: BMC Cell Biology 2017 18:20

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  14. Content type: Research article

    Environmental stress can affect the viability or fecundity of an organism. Environmental stressors may affect the genome or the proteome and can cause cellular distress by contributing to protein damage or mis...

    Authors: Katherine M. Sampuda, Mason Riley and Lynn Boyd

    Citation: BMC Cell Biology 2017 18:18

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  15. Content type: Research article

    The murine double minute 2 (MDM2) is an oncogene and a negative regulator of the tumor suppressor protein p53. MDM2 is known to be amplified in numerous human cancers, and upregulation of MDM2 is considered to be...

    Authors: Johanna Huun, Liv B. Gansmo, Bård Mannsåker, Gjertrud Titlestad Iversen, Jan Inge Øvrebø, Per E. Lønning and Stian Knappskog

    Citation: BMC Cell Biology 2017 18:17

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  16. Content type: Research article

    In Drosophila early post-meiotic spermatids, mitochondria undergo dramatic shaping into the Nebenkern, a spherical body with complex internal structure that contains two interwrapped giant mitochondrial derivativ...

    Authors: Eric M. Sawyer, Elizabeth C. Brunner, Yihharn Hwang, Lauren E. Ivey, Olivia Brown, Megan Bannon, Dennis Akrobetu, Kelsey E. Sheaffer, Oshauna Morgan, Conroy O. Field, Nishita Suresh, M. Grace Gordon, E. Taylor Gunnell, Lindsay A. Regruto, Cricket G. Wood, Margaret T. Fuller…

    Citation: BMC Cell Biology 2017 18:16

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  17. Content type: Research article

    Volumetric muscle loss caused by trauma or after tumour surgery exceeds the natural regeneration capacity of skeletal muscle. Hence, the future goal of tissue engineering (TE) is the replacement and repair of ...

    Authors: R. Witt, A. Weigand, A. M. Boos, A. Cai, D. Dippold, A. R. Boccaccini, D. W. Schubert, M. Hardt, C. Lange, A. Arkudas, R. E. Horch and J. P. Beier

    Citation: BMC Cell Biology 2017 18:15

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  18. Content type: Research article

    DNA hypermethylation is a key epigenetic mechanism for the silencing of many genes in cancer. Hinokitiol, a tropolone-related natural compound, is known to induce apoptosis and cell cycle arrest and has anti-i...

    Authors: Jung Seon Seo, Young Ha Choi, Ji Wook Moon, Hyeon Soo Kim and Sun-Hwa Park

    Citation: BMC Cell Biology 2017 18:14

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  19. Content type: Research article

    Cell-based therapy is a treatment method in tendon injuries. Bone morphogenic protein 12 (BMP-12) possesses tenogenic activity and was proposed as a differentiating factor for stem cells directed to transplant...

    Authors: Weronika Zarychta-Wiśniewska, Anna Burdzinska, Agnieszka Kulesza, Kamila Gala, Beata Kaleta, Katarzyna Zielniok, Katarzyna Siennicka, Marek Sabat and Leszek Paczek

    Citation: BMC Cell Biology 2017 18:13

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  20. Content type: Research article

    Dental pulp stem cells (DPSCs) are increasingly being recognized as a viable cell source for regenerative medicine. Although significant variations in their ex vivo expansion are well-established, DPSC prolife...

    Authors: Amr Alraies, Nadia Y. A. Alaidaroos, Rachel J. Waddington, Ryan Moseley and Alastair J. Sloan

    Citation: BMC Cell Biology 2017 18:12

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  21. Content type: Research article

    To cause an economically important blast disease on rice, the filamentous fungus Magnaporthe oryzae forms a specialized infection structure, called an appressorium, to penetrate host cells. Once inside host cells...

    Authors: Emma N. Shipman, Kiersun Jones, Cory B. Jenkinson, Dong Won Kim, Jie Zhu and Chang Hyun Khang

    Citation: BMC Cell Biology 2017 18:11

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  22. Content type: Research article

    Sprouting angiogenesis requires vascular endothelial proliferation, migration and morphogenesis. The process is regulated by soluble factors, principally vascular endothelial growth factor (VEGF), and via bidi...

    Authors: M. Jarad, E. A. Kuczynski, J. Morrison, A. M. Viloria-Petit and B. L. Coomber

    Citation: BMC Cell Biology 2017 18:10

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  23. Content type: Research

    Obstructive sleep apnea has been linked to the development of heart disease and arrhythmias, including atrial fibrillation. Since altered conduction through gap junction channels can contribute to the pathogen...

    Authors: Joanna Gemel, Zihan Su, Alex Gileles-Hillel, Abdelnaby Khalyfa, David Gozal and Eric C. Beyer

    Citation: BMC Cell Biology 2017 18(Suppl 1):7

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    This article is part of a Supplement: Volume 18 Supplement 1

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