Fig. 10From: Mice lacking DIO3 exhibit sex-specific alterations in circadian patterns of corticosterone and gene expression in metabolic tissuesSummary of the circadian disruptions (highlighted in red arrows and boxes) caused by DIO3 deficiency. Dio3-/- flattened or completely erased the circadian rhythm of gene expression in different tissues by T3 effects through the hypothalamic-pituitary-adrenal (HPA) axis without disrupting the circadian rhythm of clock genes in the specific mouse tissueBack to article page