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Fig. 1 | BMC Molecular and Cell Biology

Fig. 1

From: Mechanical stretch leads to increased caveolin-1 content and mineralization potential in extracellular vesicles from vascular smooth muscle cells

Fig. 1

Effect of mechanical strain on subcellular localization of caveolin-1 in vascular smooth muscle cells (VSMCs). A Representative western blots showing caveolin-1 (Cav-1) protein levels in caveolar (fraction 1) and non-caveolar (fraction 7) membrane fractions isolated from non-stretched VSMCs and VSMCs exposed to 10% cyclic stretch for 72 h. B Densitometry analysis of Cav-1 revealed that cyclic stretch induced a significant translocation of Cav-1 from the caveolar fraction to the non-caveolar fraction compared to non-stretched control cells n = 3 (*P < 0.05, ***P < 0.001). Data represents mean ± SD. Full-length blots are presented in Supplementary Fig. 1

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BMC Molecular and Cell Biology

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