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Fig. 5 | BMC Molecular and Cell Biology

Fig. 5

From: Optimizing combination therapy in prostate cancer: mechanistic insights into the synergistic effects of Paclitaxel and Sulforaphane-induced apoptosis

Fig. 5

shows the effect of PTX, SFN, or PTX + SFN treatments on the expression of Bax and Bcl2 proteins in PC-3 and LNCaP cells. A The Western blot and densitometric analysis histograms demonstrate significant differences between non-stimulated cells (NS) and PTX, SFN, or PTX + SFN-treated cells. B The Bax:Bcl2 ratios in PC-3 and LNCaP cells are significantly increased with PTX, SFN, or PTX + SFN treatments. The statistical analysis presented demonstrates the significance of the differences observed. The data provide further support for the additive effects of PTX and SFN on inducing apoptosis in prostate cancer cells. (**p ≤ 0.01, ***p ≤ 0.001)

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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