Fig. 2

shows the synergistic effect of SFN and PTX on reducing cell viability in PC-3 cells. The EC₅₀ value of the combined treatment was determined by treating cells with equal concentrations of  PTX and SFN and conducting the MTT cell viability assay 24 h after treatment. The data were obtained from five independent experiments and are presented as mean values with ± SD error bars in (A) or box-and-whisker plots in (B). Student’s t-test was used to determine the significant difference between PTX and PTX + SFN or between SFN and PTX + SFN. The data show that the combination treatment of SFN and PTX had a synergistic effect on reducing cell viability in PC-3 cells. (*p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001)