Table 4 Mean difference (95% CI) of mtDNAcn across quartiles of carnitine (HMDB0000062) in study patients, stratified by age
From: Association between plasma L-carnitine levels and mitochondrial DNA copy number
N | Q1 | Q2 | Q3 | Q4 | P1 | P interaction | |
|---|---|---|---|---|---|---|---|
Overall | |||||||
MV-adj model | 538 | ref | − 0.21(-0.44, 0.01) | − 0.20(-0.43, 0.03) | − 0.23(-0.45, − 0.00) | 0.06 | |
Age = < median (67 yrs) | 269 | ref | − 0.26(-0.59, 0.08) | − 0.39(-0.72, − 0.06) | − 0.33(-0.66, − 0.003) | 0.02 | 0.08 |
Age > median (67 yrs) | 269 | ref | − 0.13(-0.44, 0.17) | 0.04(-0.28, 0.37) | − 0.16(-0.49, 0.17) | 0.73 | |
Control | |||||||
MV-adj model | 280 | ref | − 0.33(-0.64, − 0.02) | − 0.21(-0.54, 0.12) | − 0.40(-0.72, − 0.08) | 0.03 | |
Age = < median (67 yrs) | 138 | ref | − 0.39(-0.87, 0.09) | − 0.55(-1.0, − 0.08) | − 0.48(-0.99, 0.03) | 0.03 | 0.12 |
Age > median (67 yrs) | 142 | ref | − 0.21(-0.62, 0.20) | 0.30(-0.17, 0.76) | − 0.34(-0.75, 0.07) | 0.32 |