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Table 3 Mean difference (95% CI) of mtDNAcn across quartiles of carnitine (HMDB0000062) in study patients

From: Association between plasma L-carnitine levels and mitochondrial DNA copy number

 

N

Q1

Q2

Q3

Q4

Nominal

P for trend

Overall

      

Age-adj model

538

ref

− 0.20 (-0.42, 0.03)

− 0.25 (-0.47, − 0.02)

− 0.26 (-0.48, − 0.03)

0.02

MV-adj model

538

ref

− 0.21 (-0.44, 0.01)

− 0.20 (-0.43, 0.03)

− 0.23 (-0.45, − 0.00)

0.06

Control

      

Age-adj model

280

ref

− 0.31 (-0.63, 0.00)

− 0.28 (-0.60, 0.04)

− 0.38 (-0.70, − 0.06)

0.02

MV-adj model

280

ref

− 0.33 (-0.64, − 0.02)

− 0.21 (-0.54, 0.12)

− 0.40 (-0.72, − 0.08)

0.03

  1. Notes: covariates adjusted in MV model include age at blood collection, fasting status, case-control status, body mass index (continuous), physical activity (continuous), smoking status (never, former, or current smokers), alcohol consumption (continuous), Alternate Health Eating Index (continuous), and histories of diabetes, cardiovascular diseases, and hypercholesterolemia. P is for p-value