From network analysis to experimental validation: identification of regulators of non-muscle myosin II contractility using the folded-gastrulation signaling pathway

Table 1 Data sources used to build the fly interactome

Data Source	Data Source Type	# Interactions^a
FlyMine [25]	Data warehouse for functional genomic & proteomic datasets	278,370
DroID [26]	Experimentally detected interactions curated from literature and external databases	262,179
Mentha [27]	Experimentally detected physical interactions	45,669
MyProteinNet [28]	Protein interaction data compiled from 11 PPI databases	41,530
SignaLink 2 [29]	Protein interactions curated from literature, integration of interactions from PPI databases, and integration of transcription factors and their regulatory interactions	5,236
FlyReactome [30]	Expert-authored knowledgebase of reactions and pathways	612

ISSN: 2661-8850