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Fig. 1 | BMC Molecular and Cell Biology

Fig. 1

From: Knockdown of ELF4 aggravates renal injury in ischemia/reperfusion mice through promotion of pyroptosis, inflammation, oxidative stress, and endoplasmic reticulum stress

Fig. 1

In kidney tissues of I/R mice and cells of OGD/R, ELF4 expression was decreased. A ELF4 mRNA expression was detected by way of qRT-PCR in kidney tissues of sham and I/R mice. ELF4 protein expression in kidney tissues of sham and I/R mice was surveyed using western blot (B) and immunohistochemistry (C). D In kidney tissues of WT and ELF4−/− mice, ELF4 protein change was ascertained using western blot. E ELF4 mRNA expression was surveyed by way of qRT-PCR in HK-2 cells. F In HK-2 cells, western blot was applied to survey ELF4 protein expression. G ELF4 mRNA expression was surveyed by way of qRT-PCR in HK-2 cells. H In HK-2 cells, ELF4 protein expression was checked by way of western blot. Mouse n = 5. Cell n = 3. * p < 0.05 vs sham, WT, or control group; # p < 0.05 vs OGD/R group

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