Table 2 The interactions between the GRP78 and PEP 35 analyzed using PDBePISA
From: A computational peptide model induces cancer cells’ apoptosis by docking Kringle 5 to GRP78
PEP 35-GRP78 complex | |||||
|---|---|---|---|---|---|
Hydrogen bonds | Salt bridges | ||||
GRP78 residue | Peptide residue | Distance (Ao) | GRP78 residue | Peptide residue | Distance (Ao) |
ASP 105 | ASN 6 | 2.11 | ASP 333 | ARG 12 | 3.82 |
GLN 109 | TYR 19 | 2.24 | LYS 340 | ASP 1 | 2.76 |
LYS 113 | ASN 18 | 1.67 | LYS 340 | ASP 1 | 2.52 |
LYS 113 | TYR 19 | 1.65 | LYS 344 | ASP 1 | 2.91 |
ARG 261 | ARG 12 | 1.81 | LYS 344 | ASP 1 | 3.36 |
ASP 333 | ARG 12 | 2.12 | LYS 470 | ASP 29 | 3.82 |
ASP 333 | ARG 12 | 1.76 | |||
SER 337 | ARG 12 | 2.16 | |||
LYS 340 | ASP 1 | 1.88 | |||
LYS 340 | ASP 1 | 1.76 | |||
LYS 344 | ASP 1 | 2.33 | |||
LYS 344 | ASP 1 | 2.38 | |||
LYS 344 | ASP 1 | 1.91 | |||
LYS 344 | MET 3 | 1.66 | |||
GLU 465 | ALA 35 | 2.02 | |||
GLU 466 | CYS 33 | 2.14 | |||
LYS 470 | LYS 8 | 1.74 | |||
ASP 471 | CYS 33 | 3.80 | |||
ASN 472 | LYS 8 | 1.76 | |||