Fig. 1
From: The STRIPAK complex components FAM40A and FAM40B regulate endothelial cell contractility via ROCKs
FAM40A and FAM40B interact with CCM3. a Schematic showing key components of the human STRIPAK complex. b COS7 cells were co-transfected with pDESTHA (empty vector) or pHA-FAM40A or pHA-FAM40B, and pmyc-CCM3. After 48 h, cells were lysed and whole cell lysates incubated with anti-HA epitope agarose beads. Proteins interacting with the HA-FAM40 proteins were visualized by immunoblotting with an antibody to the myc epitope. Lanes are taken from the same immunoblot. Immunoblots are representative of results from 3 independent experiments