Fig. 1From: Activity-dependent plasticity of electrical synapses: increasing evidence for its presence and functional roles in the mammalian brainInteractions between glutamatergic and electrical synapses that leads to activity-dependent potentiation of electrical transmission. a At goldfish mixed synapses the activity of co-existing glutamatergic synapses leads to activation of NMDARs which initiates changes in electrical (and chemical) transmission [the second form of activity-dependent potantiation involvimg mGluRs, endocannabinoids and dopamine is not represented]. b, At mammals, activation of mGluRs or NMDARs, including extrasynaptic NMDARs (eNMDAR), leads to changes in electrical transmissionBack to article page