Skip to content


Open Access

Hypothesis: could the signalling function of membrane microdomains involve a localized transition of lipids from liquid to solid state?

BMC Cell Biology20045:3

Received: 07 October 2003

Accepted: 19 January 2004

Published: 19 January 2004

Back to article

Archived Comments

  1. Question of Function

    29 January 2004

    Klaus Fiedler, Biozentrum, Basel, Switzerland

    I suggest that a biomembrane in a solid phase does not support biosynthesis and does not allow ion channel function. The latter is directly important for signaling and vesicular traffic.

    Competing interests

    None declared

Authors’ Affiliations

IFR 30, U563 INSERM, CHU Purpan, Toulouse, France