Figure 6
From: Intracellular trafficking as a determinant of AS-DACA cytotoxicity in rhabdomyosarcoma cells
AS-DACA (1 μM) penetrates further into spheroids made from the RH30 sensitive cell line. Confocal images of AS-DACA diffusion into spheroids made from the RD and RH30 cell lines after 4 and 24 h. Fluorescence intensity is shown as % Relative Fluorescence Intensity compared to distance penetrated into the spheroid for localization in the nucleus and in cytoplasmic vesicles.