Table 1 Summary of chromosomal aberrations observed in cancer cells and normal cells with or without Ag-np treatment
IMR-90 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Ag-NP µg/mL | Metaphases analysed | chromosome number | Fragments | breaks | Fusions | Total aberrations per cell | Aberrant cells (%) | ||
|  |  | (Mean ± s.e.) | acentric | centric |  |  |  | (Mean ± s.e.) |  |
| Â | Â | Â | Â | Â | Â | ring | dicentric | Â | Â |
0 | 50 | 46 ± 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
25 | 50 | 46 ± 0 | 4 | 1 | 0 | 0 | 0 | 0.094 ± 0.042 | 10% |
U251 | |||||||||
Ag-NP μg/mL | Metaphases analysed | chromosome number | fragments | breaks | fusions | Total aberrations per cell | Aberrant cells (%) | ||
|  |  | (Mean ± s.e.) | acentric | centric |  |  |  | (Mean ± s.e.) |  |
| Â | Â | Â | Â | Â | Â | ring | dicentric | Â | Â |
0 | 50 | 93 ± 2.25 | 0 | 1 | 0 | 0 | 8 | 0.18 ± 0.062 | 16% |
25 | 50 | 96 ± 2.46 | 6 | 3 | 0 | 0 | 7 | 0.32 ± 0.097 | 20% |