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Page 18 of 18

  1. Content type: Research article

    The first type III repeat of fibronectin is known to be involved in fibronectin matrix assembly, and recombinant proteins from this type III repeat can inhibit cell proliferation, tumor metastasis and angiogen...

    Authors: Kwesi O Mercurius and Alex O Morla

    Citation: BMC Cell Biology 2001 2:18

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  2. Content type: Research article

    Although MP20 is the second most highly expressed membrane protein in the lens its function remains an enigma. Putative functions for MP20 have recently been inferred from its assignment to the tetraspanin sup...

    Authors: Tamir Gonen, Angus C Grey, Marc D Jacobs, Paul J Donaldson and Joerg Kistler

    Citation: BMC Cell Biology 2001 2:17

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  3. Content type: Research article

    SPARC is a matricellular protein involved in cell-matrix interactions. From expression patterns at the wound site and in vitro studies, SPARC has been implicated in the control of wound healing. Here we examin...

    Authors: Amitabha Basu, Lorraine H Kligman, Stefan J Samulewicz and Chin C Howe

    Citation: BMC Cell Biology 2001 2:15

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  4. Content type: Research article

    The tissue accumulation of protein-bound advanced glycation endproducts (AGE) may be involved in the etiology of diabetic chronic complications, including osteopenia. The aim of this study was to investigate t...

    Authors: Antonio D McCarthy, Susana B Etcheverry, Liliana Bruzzone, Gabriela Lettieri, Daniel A Barrio and Ana M Cortizo

    Citation: BMC Cell Biology 2001 2:16

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  5. Content type: Research article

    Bone morphogenetic proteins (BMPs) and transforming growth factor-βs (TGF-βs) are important regulators of bone repair and regeneration. BMP-2 and TGF-β1 have been shown to inhibit gap junctional intercellular ...

    Authors: Lance E Wyatt, Chi Y Chung, Brian Carlsen, Akiko Iida-Klein, George H Rudkin, Kenji Ishida, Dean T Yamaguchi and Timothy A Miller

    Citation: BMC Cell Biology 2001 2:14

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  6. Content type: Research article

    Filopodia, retraction fibers and microvilli, are fragile microextensions of the plasma membrane that are easily damaged by mechanical force during specimen preparation for microscopy. To preserve these structu...

    Authors: Fumihiko Nakamura

    Citation: BMC Cell Biology 2001 2:10

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  7. Content type: Research article

    Dictyostelium cells exhibit an unusual response to hyperosmolarity that is distinct from the response in other organisms investigated: instead of accumulating compatible osmolytes as it has been described for a w...

    Authors: Tanja Pintsch, Michel Satre, Gérard Klein, Jean-Baptiste Martin and Stephan C Schuster

    Citation: BMC Cell Biology 2001 2:9

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  8. Content type: Research article

    Dimerization is an important regulatory mechanism of single membrane-spanning receptors. For instance, activation of receptor protein-tyrosine kinases (RPTKs) involves dimerization. Structural, functional and ...

    Authors: Leon GJ Tertoolen, Christophe Blanchetot, Guoqiang Jiang, John Overvoorde, Theodorus WJ Gadella Jr, Tony Hunter and Jeroen den Hertog

    Citation: BMC Cell Biology 2001 2:8

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  9. Content type: Research article

    Ethylene is a widely distributed alkene product which is formed enzymatically (e.g., in plants) or by photochemical reactions (e.g., in the upper oceanic layers from dissolved organic carbon). This gaseous com...

    Authors: Sanja Perovic, Jürgen Seack, Vera Gamulin, Werner EG Müller and Heinz C Schröder

    Citation: BMC Cell Biology 2001 2:7

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  10. Content type: Research article

    In most cells glucocorticoid receptors (GR) reside predominately in the cytoplasm. Upon hormone binding, the GR translocates into the nucleus, where the hormone-activated GR-complex regulates the transcription...

    Authors: David A Dean, Gudrun Urban, Ileana V Aragon, Mark Swingle, Beth Miller, Sandro Rusconi, Manuel Bueno, Nicholas M Dean and Richard E Honkanen

    Citation: BMC Cell Biology 2001 2:6

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  11. Content type: Research article

    Numerous investigations demonstrate a novel role of thyroid hormone as a modulator of signal transduction. Protein kinase C (PKC) is critical to the mechanism by which thyroid hormones potentiate both the anti...

    Authors: Nataliya S Kavok, Oksana A Krasilnikova and Nataliya A Babenko

    Citation: BMC Cell Biology 2001 2:5

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  12. Content type: Research article

    A breakthrough in the understanding of centriole assembly was provided by the characterization of the UNI3 gene in Chlamydomonas. Deletion of this gene, found to encode a novel member of the tubulin superfamily, ...

    Authors: Nicole Garreau de Loubresse, Françoise Ruiz, Janine Beisson and Catherine Klotz

    Citation: BMC Cell Biology 2001 2:4

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  13. Content type: Research article

    Although the role of the osteoclast in bone resorption is becoming better understood, much remains to be learned about osteoclastogenesis and the exact mechanism of action of anti-resorbing agents such as 17β-...

    Authors: Helen E Gruber, Igor J Puzanov, Michael Bennett, Vinay Kumar and Brian Gordon

    Citation: BMC Cell Biology 2001 2:3

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  14. Content type: Research article

    Aside from muscle, brain is also a major expression site for dystrophin, the protein whose abnormal expression is responsible for Duchenne muscular dystrophy. Cognitive impairments are frequently associated wi...

    Authors: Kevin Culligan, Louise Glover, Paul Dowling and Kay Ohlendieck

    Citation: BMC Cell Biology 2001 2:2

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  15. Content type: Research article

    Atherosclerosis and coronary heart disease (CHD) are significant contributors to morbidity and mortality in developed countries. A noted exception is the low mortality of CHD in France, particularly the southw...

    Authors: Jed L Bruder, Tze-chen Hsieh, Kenneth M Lerea, Susan C Olson and Joseph M Wu

    Citation: BMC Cell Biology 2001 2:1

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  16. Content type: Methodology article

    The hepatic stellate cell is the primary cell type responsible for the excessive formation and deposition of connective tissue elements during the development of hepatic fibrosis in chronically injured liver. ...

    Authors: Ralf Weiskirchen, Jens Kneifel, Sabine Weiskirchen, Eddy van de Leur, Dagmar Kunz and Axel M Gressner

    Citation: BMC Cell Biology 2000 1:4

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  17. Content type: Research article

    In eukaryotic cells, proteins are translocated across the ER membrane through a continuous ribosome-translocon channel. It is unclear to what extent proteins can fold already within the ribosome-translocon cha...

    Authors: Ismael Mingarro, IngMarie Nilsson, Paul Whitley and Gunnar von Heijne

    Citation: BMC Cell Biology 2000 1:3

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  18. Content type: Research article

    The cell surface undergoes continuous change during cell movement. This is characterized by transient protrusion and partial or complete retraction of microspikes, filopodia, and lamellipodia. This requires a ...

    Authors: Pninit Litman, Manuel Ricardo Amieva and Heinz Furthmayr

    Citation: BMC Cell Biology 2000 1:1

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