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Directional sensing and cell motility

Directional sensing and cell motility

This section will consider submissions with focus on the organization and regulation of the cellular architecture, cytoskeletal dynamics and extracellular matrix in the context of cellular directional sensing and motility.

  1. Content type: Research article

    Mesenchymal stem cells (MSCs) are multipotent stromal cells that have the ability to self-renew and migrate to sites of pathology. In vivo tracking of MSCs provides insights into both, the underlying mechanism...

    Authors: Yu Meng, Changzhen Shi, Bo Hu, Jian Gong, Xing Zhong, Xueyin Lin, Xinju Zhang, Jun Liu, Cong Liu and Hao Xu

    Citation: BMC Cell Biology 2017 18:24

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  2. Content type: Research article

    In Dictyostelium discoideum, vesicular transport of the adenylyl cyclase A (ACA) to the posterior of polarized cells is essential to relay exogenous 3′,5′-cyclic

    Authors: Satarupa Das, Joshua M. Parker, Can Guven, Weiye Wang, Paul W. Kriebel, Wolfgang Losert, Daniel R. Larson and Carole A. Parent

    Citation: BMC Cell Biology 2017 18:23

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  3. Content type: Research article

    Formins are a highly conserved family of cytoskeletal remodeling proteins. A growing body of evidence suggests that formins play key roles in the progression and spread of a variety of cancers. There are 15 hu...

    Authors: Christine Péladeau, Allan Heibein, Melissa T. Maltez, Sarah J. Copeland and John W. Copeland

    Citation: BMC Cell Biology 2016 17:32

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  4. Content type: Research article

    ADF/cofilin proteins are key modulators of actin dynamics in metastasis and invasion of cancer cells. Here we focused on the roles of ADF and cofilin-1 individually in the development of polarized migration of...

    Authors: Lubna H Tahtamouni, Alisa E Shaw, Maram H Hasan, Salem R Yasin and James R Bamburg

    Citation: BMC Cell Biology 2013 14:45

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  5. Content type: Research article

    Protein Ser/Thr Phosphatase PPP1CC2 is an alternatively spliced isoform of PPP1C that is highly enriched in testis and selectively expressed in sperm. Addition of the phosphatase inhibitor toxins okadaic acid ...

    Authors: Luis Korrodi-Gregório, Mónica Ferreira, Ana Paula Vintém, Wenjuan Wu, Thorsten Muller, Katrin Marcus, Srinivasan Vijayaraghavan, David L Brautigan, Odete A B da Cruz e Silva, Margarida Fardilha and Edgar F da Cruz e Silva

    Citation: BMC Cell Biology 2013 14:15

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  6. Content type: Research article

    AmpA is a secreted 24Kd protein that has pleiotropic effects onDictyostelium development. Null mutants delay development atthe mound stage with cells adhering too tightly to the substrate. Prestalkcells initially...

    Authors: Elizabeth F Noratel, Chere’ L Petty, Jessica S Kelsey, Hoa N Cost, Nisha Basappa and Daphne D Blumberg

    Citation: BMC Cell Biology 2012 13:29

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  7. Content type: Research article

    SM22 has long been studied as an actin-associated protein. Interestingly, levels of SM22 are often reduced in tumour cell lines, while they are increased during senescence possibly indicating a role for SM22 i...

    Authors: Oliver Thompson, Jeelan S Moghraby, Kathryn R Ayscough and Steve J Winder

    Citation: BMC Cell Biology 2012 13:1

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  8. Content type: Research article

    Many rapidly developing systems rely on the regulated translation of stored transcripts for the formation of new proteins essential for morphogenesis. The microspores of the water fern Marsilea vestita dehydrate ...

    Authors: Thomas C Boothby and Stephen M Wolniak

    Citation: BMC Cell Biology 2011 12:45

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  9. Content type: Research article

    In a motile polarized cell the actin system is differentiated to allow protrusion at the front and retraction at the tail. This differentiation is linked to the phosphoinositide pattern in the plasma membrane....

    Authors: Günther Gerisch, Mary Ecke, Dirk Wischnewski and Britta Schroth-Diez

    Citation: BMC Cell Biology 2011 12:42

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  10. Content type: Research article

    In most cells, the centriolar component of the centrosome can function as a basal body supporting the formation of a primary cilium, a non-motile sensory organelle that monitors information from the extracellu...

    Authors: Joanna J Moser, Marvin J Fritzler and Jerome B Rattner

    Citation: BMC Cell Biology 2011 12:37

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  11. Content type: Research article

    Chondromodulin-I (ChM-I) is an anti-angiogenic glycoprotein that is specifically localized at the extracellular matrix of the avascular mesenchyme including cartilage and cardiac valves. In this study, we char...

    Authors: Shigenori Miura, Chisa Shukunami, Kaori Mitsui, Jun Kondo and Yuji Hiraki

    Citation: BMC Cell Biology 2011 12:34

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  12. Content type: Research article

    Different types of membrane microdomains (rafts) have been postulated to be present in the rear and front of polarized migrating T-lymphocytes. Disruption of rafts by cholesterol sequestration prevents T-cell ...

    Authors: Sarah Affentranger, Sibylla Martinelli, Jonas Hahn, Jérémie Rossy and Verena Niggli

    Citation: BMC Cell Biology 2011 12:28

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  13. Content type: Research article

    Motile cilia are essential to the survival and reproduction of many eukaryotes; they are responsible for powering swimming of protists and small multicellular organisms and drive fluids across respiratory and ...

    Authors: Margarida Ressurreição, David Rollinson, Aidan M Emery and Anthony J Walker

    Citation: BMC Cell Biology 2011 12:6

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