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Cell signaling pathways and networks

This section will consider submissions on cell signaling, cell-cell interaction, second messenger systems and receptor-mediated signaling.

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  1. Content type: Database

    Research antibodies are used by thousands of scientists working in diverse disciplines, but it is common to hear concerns about antibody quality. This means that researchers need to carefully choose the antibo...

    Authors: Matthew A Helsby, Paul M Leader, Joe R Fenn, Tulay Gulsen, Chris Bryant, Gail Doughton, Ben Sharpe, Paul Whitley, Christopher J Caunt, Katrina James, Adam D Pope, Dave H Kelly and Andrew D Chalmers

    Citation: BMC Cell Biology 2014 15:6

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  2. Content type: Research article

    Reduced muscle mass is a hallmark of metabolic diseases like diabetes and cancer. The mammalian (mechanistic) target of rapamycin complex 1/S6 kinase 1 (mTORC1/S6K1) pathway is critical to the regulation of mu...

    Authors: Dhanshri Kakade, Nushaba Islam, Naomi Maeda and Olasunkanmi A J Adegoke

    Citation: BMC Cell Biology 2014 15:2

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  3. Content type: Research article

    Integrin α6β4 contributes to cancer progression by stimulating transcription as well as translation of cancer related genes. Our previous study demonstrated that α6β4 stimulates translation initiation of survi...

    Authors: Young Hwa Soung, Nadejda Korneeva, Tae Hyong Kim and Jun Chung

    Citation: BMC Cell Biology 2013 14:49

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  4. Content type: Research article

    Casein Kinase 1 (CK1) is one of few proteins known to affect cellular timekeeping across metazoans, and the naturally occurring CK1tau mutation shortens circadian period in mammals. Functional conservation of a t...

    Authors: Gerben van Ooijen, Sarah F Martin, Martin E Barrios-Llerena, Matthew Hindle, Thierry Le Bihan, John S O'Neill and Andrew J Millar

    Citation: BMC Cell Biology 2013 14:46

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  5. Content type: Research article

    Differentiation and fusion of skeletal muscle myoblasts into multi-nucleated myotubes is required for neonatal development and regeneration in adult skeletal muscle. Herein, we report novel findings that prote...

    Authors: Joseph S Marino, Terry D Hinds Jr., Rachael A Potter, Eric Ondrus, Jeremy L Onion, Abigail Dowling, Thomas J McLoughlin, Edwin R Sanchez and Jennifer W Hill

    Citation: BMC Cell Biology 2013 14:39

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  6. Content type: Methodology article

    Tissue microenvironments comprise different extracellular matrix (ECM) proteins that regulate cellular responsiveness to growth factors. In vitro culture of adherent cells on ECM-coated substrata is commonly u...

    Authors: Iren Abrahamsen and James B Lorens

    Citation: BMC Cell Biology 2013 14:36

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  7. Content type: Research article

    The transcription factor E2F4 controls proliferation of normal and cancerous intestinal epithelial cells. E2F4 localization in normal human intestinal epithelial cells (HIEC) is cell cycle-dependent, being cyt...

    Authors: Marie-Christine Paquin, Sébastien Cagnol, Julie C Carrier, Caroline Leblanc and Nathalie Rivard

    Citation: BMC Cell Biology 2013 14:33

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  8. Content type: Research article

    In the progression towards diabetes, glucolipotoxicity is one of the main causes of pancreatic beta cell pathology. The aim of this study was to examine the in vitro effects of chronic glucolipotoxic conditions o...

    Authors: Baggavalli P Somesh, Mahesh Kumar Verma, Manoj Kumar Sadasivuni, Anup Mammen-Oommen, Sanghamitra Biswas, Pavagada C Shilpa, Ashok Kumar Reddy, Aggunda N Yateesh, Puttrevana M Pallavi, Siddaraju Nethra, Rachapalli Smitha, Korrapati Neelima, Usha Narayanan and Madanahalli R Jagannath

    Citation: BMC Cell Biology 2013 14:31

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  9. Content type: Research article

    The transition of epithelial cells from their normal non-motile state to a motile one requires the coordinated action of a number of small GTPases. We have previously shown that epithelial cell migration is st...

    Authors: Myriam A Attar and Lorraine C Santy

    Citation: BMC Cell Biology 2013 14:9

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  10. Content type: Research article

    Rap proteins belong to the Ras family of small G-proteins. Dictyostelium RapA is essential and implicated in processes throughout the life cycle. In early development and chemotaxis competent cells RapA induces p...

    Authors: Katarzyna Plak, Douwe Veltman, Fabrizia Fusetti, Jetze Beeksma, Francisco Rivero, Peter JM Van Haastert and Arjan Kortholt

    Citation: BMC Cell Biology 2013 14:6

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  11. Content type: Research article

    The mammalian target of rapamycin (mTOR) signalling pathway has a key role in cellular regulation and several diseases. While it is thought that Rheb GTPase regulates mTOR, acting immediately upstream, while r...

    Authors: Rahul B Yadav, Pierre Burgos, Anthony W Parker, Valentina Iadevaia, Christopher G Proud, Rodger A Allen, James P O'Connell, Ananya Jeshtadi, Christopher D Stubbs and Stanley W Botchway

    Citation: BMC Cell Biology 2013 14:3

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  12. Content type: Research article

    Hyperleptinemia is known to participate in cardiac hypertrophy and hypertension, but the relationship between pressure overload and leptin is poorly understood. We therefore examined the expression of leptin (...

    Authors: Hiroki Matsui, Tomoyuki Yokoyama, Chie Tanaka, Hiroaki Sunaga, Norimichi Koitabashi, Takako Takizawa, Masashi Arai and Masahiko Kurabayashi

    Citation: BMC Cell Biology 2012 13:37

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  13. Content type: Research article

    Transient receptor potential canonical (TRPC) channels are non-selective cation channels involved in receptor-mediated calcium signaling in diverse cells and tissues. The canonical transient receptor potential...

    Authors: Robert Carrasquillo, Dequan Tian, Sneha Krishna, Martin R Pollak, Anna Greka and Johannes Schlöndorff

    Citation: BMC Cell Biology 2012 13:33

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  14. Content type: Research article

    The Dystrophin Glycoprotein Complex (DGC) is at the center of significant inheritable diseases, such as muscular dystrophies that can be fatal and impair neuronal function in addition to muscle degeneration. R...

    Authors: April K Marrone, Evgeniia V Edeleva, Mariya M Kucherenko, Nai-Hua Hsiao and Halyna R Shcherbata

    Citation: BMC Cell Biology 2012 13:26

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  15. Content type: Research article

    Ovarian cancer is one of the most lethal malignancies in women, as it is frequently detected at an advanced stage, and cancers often become refractory to chemotherapy. Evidence suggests that dysregulation of p...

    Authors: Uttara Saran, Frank Arfuso, Nikolajs Zeps and Arunasalam Dharmarajan

    Citation: BMC Cell Biology 2012 13:25

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  16. Content type: Research article

    In interferon-γ-stimulated cells, the dimeric transcription factor STAT1 (s ignal t ransducer and a ctivator of t ranscription 1) recognizes semi-palindromic motifs in the promoter regions of cytokine-driven targ...

    Authors: Verena Koch, Julia Staab, Volker Ruppert and Thomas Meyer

    Citation: BMC Cell Biology 2012 13:22

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  17. Content type: Research article

    Transforming growth factor-beta 1 (TGF-β1) has been implicated in hyperoxia-induced cell death and impaired alveolarization in the developing lung. In addition, the c-JunNH2-terminal kinase (JNK) pathway has b...

    Authors: Zhang Li, Rayman Choo-Wing, Huanxing Sun, Angara Sureshbabu, Reiko Sakurai, Virender K Rehan and Vineet Bhandari

    Citation: BMC Cell Biology 2011 12:54

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  18. Content type: Research article

    SOX4 is a developmental transcription factor that is required for differentiation and proliferation in multiple tissues. SOX4 is overexpressed in many human malignancies, but the precise role of SOX4 in cancer...

    Authors: Yu-Heng Lai, Jessica Cheng, Dongmei Cheng, Mattie E Feasel, Kyle D Beste, Junmin Peng, Asma Nusrat and Carlos S Moreno

    Citation: BMC Cell Biology 2011 12:50

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  19. Content type: Research article

    The Notch signalling pathway is conserved in pre-bilaterian animals. In the Cnidarian Hydra it is involved in interstitial stem cell differentiation and in boundary formation during budding. Experimental evidence...

    Authors: Andrea Prexl, Sandra Münder, Bernhard Loy, Elisabeth Kremmer, Susanne Tischer and Angelika Böttger

    Citation: BMC Cell Biology 2011 12:38

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  20. Content type: Research article

    Stanniocalcin 2 (STC2) is a secreted protein activated by (PKR)-like Endoplasmic Reticulum Kinase (PERK) signalling under conditions of ER stress in vitro. Over-expression of STC2 in mice leads to a growth-restri...

    Authors: Elena N Fazio, Gabriel E DiMattia, Sami A Chadi, Kristin D Kernohan and Christopher L Pin

    Citation: BMC Cell Biology 2011 12:17

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2016 Journal Metrics

  • Citation Impact
    2.405 - 2-year Impact Factor
    2.768 - 5-year Impact Factor
    0.836 - Source Normalized Impact per Paper (SNIP)
    1.351 - SCImago Journal Rank (SJR)

    1136.5 Usage Factor

    Social Media Impact
    38 Mentions