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BMC Cell Biology

Cell differentiation and proliferation

This section will consider submissions with a focus on cell culture, growth and differentiation, including stem and germ cells, multipotency and tumor invasion.

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  1. Content type: Research article

    Carcinoma associated fibroblasts (CAFs or myofibroblasts) are activated fibroblasts which participate in breast tumor growth, angiogenesis, invasion, metastasis and therapy resistance. As such, recent efforts ...

    Authors: Kathryn Woods, Catlyn Thigpen, Jennifer Peyling Wang, Hana Park and Abigail Hielscher

    Citation: BMC Cell Biology 2017 18:35

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  2. Content type: Research article

    Self-renewal and differentiation of embryonic stem cells (ESCs) is directed by biological and/or physical cues that regulate multiple signaling cascades. We have previously shown that mESCs seeded in a type I ...

    Authors: Olesja Hazenbiller, Neil A. Duncan and Roman J. Krawetz

    Citation: BMC Cell Biology 2017 18:32

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  3. Content type: Methodology article

    Generalized methods for understanding the cell biology of non-model species are quite rare, yet very much needed. In order to address this issue, we have modified a technique traditionally used in the biomedic...

    Authors: Benyamin Rosental, Zhanna Kozhekbaeva, Nathaniel Fernhoff, Jonathan M. Tsai and Nikki Traylor-Knowles

    Citation: BMC Cell Biology 2017 18:30

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  4. Content type: Research article

    Cartilage degradation is the significant pathological process in osteoarthritis (OA). Inflammatory cytokines, such as interleukin-1β (IL-1β), activate various downstream mediators contributing to OA pathology....

    Authors: Hao Wu, Zhanhai Yin, Ling Wang, Feng Li and Yusheng Qiu

    Citation: BMC Cell Biology 2017 18:29

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  5. Content type: Research article

    Biomaterials are widely used to regenerate or substitute bone tissue. In order to evaluate their potential use for clinical applications, these need to be tested and evaluated in vitro with cell culture models...

    Authors: Raquel Núñez-Toldrà, Ester Martínez-Sarrà, Carlos Gil-Recio, Miguel Ángel Carrasco, Ashraf Al Madhoun, Sheyla Montori and Maher Atari

    Citation: BMC Cell Biology 2017 18:21

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  6. Content type: Research article

    External root resorption, commonly starting from cementum, is a severe side effect of orthodontic treatment. In this pathological process and repairing course followed, cementoblasts play a significant role. P...

    Authors: Yuyu Li, Zhiai Hu, Chenchen Zhou, Yang Xu, Li Huang, Xin Wang and Shujuan Zou

    Citation: BMC Cell Biology 2017 18:19

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  7. Content type: Research article

    Volumetric muscle loss caused by trauma or after tumour surgery exceeds the natural regeneration capacity of skeletal muscle. Hence, the future goal of tissue engineering (TE) is the replacement and repair of ...

    Authors: R. Witt, A. Weigand, A. M. Boos, A. Cai, D. Dippold, A. R. Boccaccini, D. W. Schubert, M. Hardt, C. Lange, A. Arkudas, R. E. Horch and J. P. Beier

    Citation: BMC Cell Biology 2017 18:15

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  8. Content type: Research article

    Cell-based therapy is a treatment method in tendon injuries. Bone morphogenic protein 12 (BMP-12) possesses tenogenic activity and was proposed as a differentiating factor for stem cells directed to transplant...

    Authors: Weronika Zarychta-Wiśniewska, Anna Burdzinska, Agnieszka Kulesza, Kamila Gala, Beata Kaleta, Katarzyna Zielniok, Katarzyna Siennicka, Marek Sabat and Leszek Paczek

    Citation: BMC Cell Biology 2017 18:13

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  9. Content type: Research article

    Dental pulp stem cells (DPSCs) are increasingly being recognized as a viable cell source for regenerative medicine. Although significant variations in their ex vivo expansion are well-established, DPSC prolife...

    Authors: Amr Alraies, Nadia Y. A. Alaidaroos, Rachel J. Waddington, Ryan Moseley and Alastair J. Sloan

    Citation: BMC Cell Biology 2017 18:12

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  10. Content type: Research article

    To cause an economically important blast disease on rice, the filamentous fungus Magnaporthe oryzae forms a specialized infection structure, called an appressorium, to penetrate host cells. Once inside host cells...

    Authors: Emma N. Shipman, Kiersun Jones, Cory B. Jenkinson, Dong Won Kim, Jie Zhu and Chang Hyun Khang

    Citation: BMC Cell Biology 2017 18:11

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  11. Content type: Research article

    Sprouting angiogenesis requires vascular endothelial proliferation, migration and morphogenesis. The process is regulated by soluble factors, principally vascular endothelial growth factor (VEGF), and via bidi...

    Authors: M. Jarad, E. A. Kuczynski, J. Morrison, A. M. Viloria-Petit and B. L. Coomber

    Citation: BMC Cell Biology 2017 18:10

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  12. Content type: Methodology article

    Karyotypic integrity is essential for the successful germline transmission of alleles mutated in embryonic stem (ES) cells. Classical methods for the identification of aneuploidy involve cytological analyses t...

    Authors: Gemma F. Codner, Loic Lindner, Adam Caulder, Marie Wattenhofer-Donzé, Adam Radage, Annelyse Mertz, Benjamin Eisenmann, Joffrey Mianné, Edward P. Evans, Colin V. Beechey, Martin D. Fray, Marie-Christine Birling, Yann Hérault, Guillaume Pavlovic and Lydia Teboul

    Citation: BMC Cell Biology 2016 17:30

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  13. Content type: Research article

    IL-27 is a multifunctional cytokine that has both pro-inflammatory and anti-inflammatory functions. Although IL-27 has been shown to potently inhibit lung fibrosis, the detailed mechanism of IL-27 in this proc...

    Authors: Zhaoxing Dong, Wenlin Tai, Wen Lei, Yin Wang, ZhenKun Li and Tao Zhang

    Citation: BMC Cell Biology 2016 17:7

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  14. Content type: Methodology article

    The traditional problems of performing skeletal muscle cell cultures derived from mammalian or avian species are limited myotube differentiation, and transient myotube persistence which greatly restricts the a...

    Authors: Sujith Sebastian, Leah Goulding, Suresh V. Kuchipudi and Kin-Chow Chang

    Citation: BMC Cell Biology 2015 16:23

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  15. Content type: Research article

    Environmental factors are important for stem cell lineage specification, and increasing evidence indicates that the nanoscale geometry/topography of the extracellular matrix (ECM) directs stem cell fate. Recen...

    Authors: Yan Chen, Di Zeng, Lu Ding, Xiao-Li Li, Xiong-Tao Liu, Wen-Ju Li, Ting Wei, Song Yan, Jiang-Hui Xie, Li Wei and Qiang-Sun Zheng

    Citation: BMC Cell Biology 2015 16:22

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  16. Content type: Research article

    Preeclampsia, one of the major disorders of pregnancy, is characterized by inadequate trophoblast invasion and defective trophoblast-mediated remodeling of placental vasculature. MicroRNA-34a (miR-34a) has bee...

    Authors: Manni Sun, Haiying Chen, Jing Liu, Chunxiao Tong and Tao Meng

    Citation: BMC Cell Biology 2015 16:21

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  17. Content type: Research article

    Mesenchymal stromal cells (MSC) can be obtained from potentially any tissue from the human body, but cells purified from different sources are undoubtedly different, and for each medical application, the MSC w...

    Authors: Paola Romina Amable, Marcus Vinicius Telles Teixeira, Rosana Bizon Vieira Carias, José Mauro Granjeiro and Radovan Borojevic

    Citation: BMC Cell Biology 2014 15:46

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  18. Content type: Methodology

    Basement matrices such as Matrigel™ and Geltrex™ are used in a variety of cell culture assays of anchorage-dependent differentiation including endothelial cell tube formation assays. The volumes of matrix reco...

    Authors: Ashton Faulkner, Robert Purcell, Andrew Hibbert, Sally Latham, Scott Thomson, Wendy L Hall, Caroline Wheeler-Jones and David Bishop-Bailey

    Citation: BMC Cell Biology 2014 15:41

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  19. Content type: Methodology article

    Endothelial-mesenchymal transition (EndoMT) has been shown to be a major source of myofibroblasts, contributing to kidney fibrosis. However, in vitro study of endothelial cells often relies on culture of isolated...

    Authors: Ye Zhao, Hong Zhao, Yun Zhang, Tania Tsatralis, Qi Cao, Ya Wang, Yiping Wang, Yuan Min Wang, Steve I Alexander, David C Harris and Guoping Zheng

    Citation: BMC Cell Biology 2014 15:40

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2016 Journal Metrics

  • Citation Impact
    2.405 - 2-year Impact Factor
    2.768 - 5-year Impact Factor
    0.836 - Source Normalized Impact per Paper (SNIP)
    1.351 - SCImago Journal Rank (SJR)

    Usage 
    311,604 Downloads
    1136.5 Usage Factor

    Social Media Impact
    38 Mentions

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